Table 1 Sensitivity, specificity and PPV of the studies
Study | Sample size | Marker | Sensitivity (%) | Specificity (%) | PPV (%) | Positive results (%) |
|---|---|---|---|---|---|---|
[57] | 12,932 | VCA-IgA EA-IgA (among positive VCA-IgA) | – | – | – | 5.3% 1.9% |
[56] | 405a | EBNA1 VCA EBNA1 + VCA | 88.6 79.8 85.4 | 80.1 70.9 90.1 | 80.6 67.7 78.7 | – |
[58] | 22,186 | Plasma EBV DNA | 87.5 | 98.9 | 41.2 | – |
[59] | 317b | IgA-VCA EBV DNA IgA-VCA + EBV DNA | 81 95 99 | 96 98 96–98 | – | – |