Fig. 6From: Transcription factor LHX9 (LIM Homeobox 9) enhances pyruvate kinase PKM2 activity to induce glycolytic metabolic reprogramming in cancer stem cells, promoting gastric cancer progressionNude Mouse Subcutaneous Tumor Model to Validate the Effect and Mechanism of LHX9 on Tumor Growth and Glycolytic Reprogramming. A: comparison of subcutaneous transplantation tumor mass in each group of nude mice; B: comparison of subcutaneous transplantation tumor volume in each group of nude mice; C: comparison of subcutaneous transplantation tumor mass in each group of nude mice; D: comparison of lactate expression in subcutaneous transplantation tumor tissue in each group of nude mice; E: comparison of ATP content in subcutaneous transplantation tumor tissue in each group of nude mice; F: comparison of glycolysis-related genes (GLUT1, HK2, LDHA F: Comparison of mRNA and protein expression of glycolysis-related genes (GLUT1, HK2, LDHA, and PDK1) in subcutaneous transplanted tumor tissues of nude mice in each group; *: P < 0.05, statistically significant between groups; An independent samples t-test was used to compare the two groups, and a repeated ANOVA was employed to analyze the tumor data at different time points (N = 10)Back to article page