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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Unveiling the dynamics of the breast milk microbiome: impact of lactation stage and gestational age

Fig. 4

Comparison of the microbiota composition and diversity in preterm and term BM samples. (A) PCoA plots showing the beta diversity measure using unweighted unifrac distances (p = 0.001); p values determined by ADONIS; Preterm: brown, Term: green. (B) Mean relative abundances of top five abundant bacterial phyla in the two groups (C) Boxplots of Alpha-diversity indices: Observed OTUs; Chao1; Shannon; Simpson; Ace; Pielou_e; Faith_pd. Boxes represent the interquartile range (IQR) between the first and third quartiles (25th and 75th percentiles, respectively), and the horizontal line inside the box defines the median. Whiskers represent the lowest and highest values within 1.5 times the IQR from the first and third quartiles, respectively. Statistical significance was identified by the Wilcoxon test with false discovery rate (FDR)-Benjamini-Hochberg (BH) corrected p values. ns = non-significant; *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001, brown: preterm, green: term. The figure was generated using (RStudio v 2022.2.3.492 with R v 4.0.5)

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