Table 1 Role of miR-1-3p in tumor occurrence and development

STC2

Gastric cancer

Inhibit the proliferation and invasion

[56]

CENPF

Gastric cancer

Inhibit the proliferation, migration, and invasion

[57]

G6PD

Gastric cancer

Inhibit the Warburg effect

Inhibit cell proliferation and promote cell apoptosis

[30]

YWHAZ

Colorectal cancer

Inhibit the proliferation and invasion

[65]

IGF1

Colorectal cancer

Inhibit the proliferation

and promote their apoptosis

[66]

NAMPT

Colorectal cancer

Form a negative feedback pathway

[70]

CENPF

Lung adenocarcinoma

Inhibit proliferation and migration

[73]

FAM83A

Lung cancer

Inhibit the proliferation, invasion, and migration

[74]

CELSR3

Lung adenocarcinoma

Inhibit the proliferation, migration, and invasion

[75]

/

Non-small cell lung cancer

Inhibit the proliferation

[29]

PAICS

Non-small cell lung cancer

Involved in the glycolysis and nucleotide metabolism

[76]

CCL2

Bladder cancer

Inhibit cell proliferation, colony formation, migration, and invasion, promote mitosis to stagnate in the G0/G1 phase, and increase the ratio of apoptosis

[83]

C1GALT1

Bladder cancer

Inhibit the proliferation and migration

[38]

GLS

Bladder cancer

Inhibit the proliferation, migration, and invasion

[88]

BDNF/TrkB

Bladder cancer

Inhibit the proliferation, migration, invasion

[94]

SOX9

Hepatocellular carcinoma

Inhibit the proliferation of HCC cells and promote their apoptosis

[99]

ORC6

Hepatocellular carcinoma

Inhibit HCC cell proliferation, migration, and invasion, and induce cell cycle arrest and apoptosis

[103]

/

Hepatocellular carcinoma

Inhibit angiogenesis

[108]

IGF1

Hepatocellular carcinoma

Inhibit the proliferation of HCC cells and promote apoptosis, and more HCC cells stay in G0/G1 phase

[25]

E2F5 and PFTK1

Prostate cancer

Inhibit the proliferation and colony forming and make more cells stay in the G0/1 phase

[111]

CORO1C

Prostate cancer

Inhibit the migration, invasion, and EMT progression

[26]

LASP1

Prostate cancer

Inhibit the proliferation and migration and bone metastasis (BM) of Gleason 3 + 4 PCa

[114]

TAGLN2

Esophageal cancer

Inhibit the proliferation, colony formation, invasion and promote apoptosis

[117]

PIK3CA/AKT pathway

Esophageal cancer

Inhibit the proliferation and promote apoptosis

[31]

CORO1C/TPM3

Esophageal cancer

Inhibit the migration and invasion

[27]

DKK1

Oral squamous cell carcinoma

Inhibit the proliferation, migration, and invasion, block the transition from the G0/G1 phase to the S phase and induce cell apoptosis

[120]

Fibronectin 1

Renal cell carcinoma

Inhibit the EMT process and weaken the ability of migration and invasion

[133]

TNKS2/Wnt/ β-catenin signaling pathway

Ovarian cancer

Inhibit the proliferation, induce cell cycle arrest in the G1/S phase, and promote cell apoptosis

[121]

c-Met

Ovarian cancer

Block cell cycle progression and inhibit proliferation, migration, and invasion of OA cells

[122]

Bcl-2

Breast cancer

Inhibit proliferation, migration, invasion and promote cell apoptosis

[127]

K-Ras and lncRNA MALAT1

Breast cancer

Inhibited cell proliferation and motility and promoted apoptosis

[128]

MEK/ERK

Breast cancer

Inhibit proliferation, migration, invasion

[129]

BVI-1

Breast cancer

Inhibit proliferation and EMT-related genes in BCSCs and promote apoptosis

[130]

MINOS1, GPD2, LRPPRC

Breast cancer

Trigger mitochondrial damage and promote mitochondrial autophagy in BCSCs

[131]

CDK14

Osteosarcoma

Inhibit cell proliferation and cell cycle progression while promoting apoptosis

[137]

Fibronectin 1

Glioblastoma

inhibit the proliferation and migration of cells

[147]

YY1

Medulloblastoma

Promote malignant phenotypes

[148]

G6PD

Pituitary tumors

Inhibit NADPH production and glycolytic processes;

Inhibit proliferation and promote apoptosis

[149]

VASP/Rap1 axis

Breast cancer

Inhibit the malignant phenotype and chemotherapy resistance of BC cells

[28]