Fig. 2

Regulation of miR-1-3p. The regulation of miR-1-3p is mainly influenced by factors such as lncRNA, circRNA, DNA promoter methylation, SNP, etc. LncRNA and circRNA can bind and silence miR-1-3p. DNA promoter methylation can inhibit the transcription of the miR-1-3p gene. SNP can affect the binding of related enzymes, thereby affecting the generation and processing of miR-1-3p. SND1 can bind and degrade miR-1-3p through the SN domain. In addition, factors such as transcription factors, histone acetylation, and gene mutations also regulate the expression level of miR-1-3p