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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: The enrichment of Fanconi anemia/homologous recombination pathway aberrations in ATM/ATR-mutated NSCLC was accompanied by unique molecular features and poor prognosis

Fig. 4

FA/HR aberrations were associated with higher nucleotide-level changes and worse prognosis in PIKK-mutated patients. A The comparison of TMB in NSCLC patients with different PIKK and FA/HR mutational statuses in the study cohort. B The comparison of CIS in NSCLC patients with different PIKK and FA/HR mutational statuses in the study cohort. C The comparison of MSI frequency in NSCLC patients with different PIKK and FA/HR mutational statuses in the study cohort. D Kaplan–Meier curve of overall survival in NSCLC patients from the external cohort in strata of different PIKK and FA/HR mutational statuses

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