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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: The enrichment of Fanconi anemia/homologous recombination pathway aberrations in ATM/ATR-mutated NSCLC was accompanied by unique molecular features and poor prognosis

Fig. 3

Fanconi anemia (FA) and homologous recombination (HR) pathway aberrations were enriched in PIKK-mutated NSCLC patients. A–C The gene ontology analysis for mutations enriched in PIKK-mutated patients than PIKK-WT patients from the study cohort. D, E The KEGG pathway analysis for mutations enriched in PIKK-mutated patients than PIKK-WT patients from the study cohort. F The analysis of co-occurring and mutually exclusive mutated genes in PIKK-mutated NSCLC patients in the study cohort. G, H) The enrichment of FA/HR pathway-related mutations in NSCLC patients with different PIKK mutational statuses for the study cohort (G) and the external cohort (H)

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Journal of Translational Medicine

ISSN: 1479-5876

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