Fig. 2

Overexpression of HOTAIRM1 promotes glioma cell proliferation, migration, invasion and VM. A qRT-PCR detected HOTAIRM1 expression level in glioma cells transfected with overexpressing HOTAIRM1 plasmid or siRNA. B CCK-8 assay was used to measure the proliferative capacity of transfected glioma cells. C–D Transwell assay detected migration and invasion capacity of transfected glioma cells (Scale bar = 50 μm). E Tube-formation assay evaluated VM capacity affected by HOTAIRM1 (Scale bar = 100 μm); Data are presented as the mean ± SD of three independent experiments (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001