Fig. 5

Simulated ex vivo lung perfusion (EVLP) did not induce genes related to inflammation and cell death in human lung endothelial and epithelial cells. A. In human pulmonary microvascular endothelial cells (HPMEC), simulation of EVLP led to downregulation of gene clusters in DNA, RNA, protein, and mitochondria themes, and no upregulated pathways were observed. B. In human lung epithelial cells (BEAS-2B), EVLP model showed downregulation in three pathways that belonged to RNA, protein, and mitochondria themes. Again, there were no upregulated pathways