Fig. 6

Prediction of chemotherapy drug sensitivity based on circulating microbiome signatures. A–H Boxplots and correlation plots of the comparison in IC50 values of Doramapimod_1042 A, SB505124_1194 B, Ribociclib_1632 C, Gefitinib_1010 D, GSK1904529A_1093 E, Crizotinib_1083 F, Dabrafenib_1373 G and KRAS (G12C) Inhibitor-12_1855 H between circulating MAPS-high and MAPS-low groups. The blue box represented circulating MAPS-high group, and the red box represented circulating MAPS-low group. I–K Boxplots and correlation plots of the comparison in IC50 values of Dabrafenib_1373 I, Crizotinib_1083 J and GSK1904529A_1093 K between circulating Candidatus_Babela-high and Candidatus_Babela-low groups. The blue box represented circulating Candidatus_Babela-low group, and the red box represented circulating Candidatus_Babela-high group. *** P < 0.001; ** P < 0.01; * P < 0.05