Table 1 Clinical characteristics of patients in the training and validation cohort
|  | Total (n = 1143) | Training (n = 617) | Validation (n = 526) | p |
|---|---|---|---|---|
Sex, n (%) | Â | Â | Â | 0.2 |
Female | 536 (46.89) | 296 (47.97) | 240 (45.63) | Â |
Male | 607 (53.11) | 321 (52.03) | 286 (54.37) | Â |
Age, Mean ± SD | 61 ± 11.7 | 61.6 ± 12.2 | 60.4 ± 11.1 | 0.075 |
Location, n (%) | Â | Â | Â | 0.014 |
Stomach | 756 (66.14) | 388 (62.88) | 368 (69.96) | Â |
Non-stomach | 387 (33.86) | 229 (37.12) | 158 (30.04) | Â |
Mitotic count (/50 HPF), n (%) | Â | Â | Â | 0.004 |
 < 5 | 897 (78.48) | 503 (81.52) | 394 (74.9) |  |
6 ~ 10 | 146 (12.77) | 75 (12.16) | 71 (13.5) |  |
 > 10 | 100 (8.75) | 39 (6.32) | 61 (11.6) |  |
Risk of aggressive behavior*, n (%) | Â | Â | Â | 0.322 |
Very low | 77 (6.74) | 49 (7.94) | 28 (5.32) | Â |
Low | 481 (42.08) | 256 (41.49) | 225 (42.78) | Â |
Intermediate | 247 (21.61) | 128 (20.75) | 119 (22.62) | Â |
High | 338 (29.57) | 184 (29.82) | 154 (29.28) | Â |
KIT-11 mutation | Â | Â | Â | 0.494 |
No mutation | 268 (23.45) | 134 (21.72) | 134 (25.48) | Â |
Point mutations or duplications | 435 (38.06) | 243 (39.38) | 192 (36.5) | Â |
Deletions not involving codons 557/558 | 197 (17.24) | 108 (17.5) | 89 (16.92) | Â |
KIT exon 11 557/558 deletions | 243 (21.26) | 132 (21.39) | 111 (21.1) | Â |