Fig. 2

Differentially expressed pyroptosis-related genes (PRGs) between SKCM tissues and normal tissues. A Volcano plot shows PRGs, with red dots indicating high expression and blue dots indicating low expression in SKCM tissues. B Heatmap of diferentially expressed PRGs, with red denoting high expression, blue denoting low expression. C Protein–protein interaction (PPI) network indicates the interaction of PRGs (interaction score = 0.4). D Correlation matrix of interaction in PRGs, with red dots indicating positive correlation, and blue dots indicating negative correlation. E Summary of alterations in differentially expressed PRGs in SKCM.