Fig.4

Chronic UVR-induced lymphatic drainage function declined in photoaging skin and restored in cSCC skin. UVR-induced drainage function of LVs assessed by Evans Blue assay in vivo. A Image of Evans Blue in the skin. B Statistics of the area of Evans Blue. Mice in the UV-0w group spent the shortest time drainage Evans Blue, UV-20-24w the second, implant SCC the third, and UV-8w the last. C Statistics of the Evans Blue grade in different time. The blue color grades in the UV-20-24w group appeared as the lightest color, UV-0w the second, and UV-8w the darkest shade. D The number of mice with some residues was shown in blue color. The horizontal axis represents time (day)