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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Suppressive stroma-immune prognostic signature impedes immunotherapy in ovarian cancer and can be reversed by PDGFRB inhibitors

Fig. 5

Correlation of SIPS with genomic instability. The boxplots showed the levels of A HRD Score, B LOH, C LST, and D TAI in patients with different SIPS subtypes in TCGA-OV cohort. E The heatmap showed the levels of the 30 most mutational signatures in patients with different SIPS subtypes. F The oncoprint showed the landscape genome changes in patients with different SIPS subtypes. G The bar plot showed the most mutated genes in patients with different SIPS subtypes. The boxplots showed the levels of SIPS score in patients with different H P53 and I BRCA1 mutational statuses in TCGA-OV cohort. J The boxplot showed the levels of tumor mutation burden in patients with different SIPS subtypes in TCGA-OV cohort. The boxplots showed the levels of K tumor mutation burden and L neoantigen in patients with different SIPS subtypes in BLCA cohort

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Journal of Translational Medicine

ISSN: 1479-5876

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