Fig. 8

The graphic abstract of JorA inhibiting MIBC. JorA plays anticancer roles mainly through repressing the proliferation and migration, and inducing apoptosis of MIBC. The green oval labeled molecules are those significantly downregulated by JorA, and the red ovals labeled molecules are those significantly upregulated by JorA. The molecules marked with yellow oval are the interacting molecules of JorA. In the insert, the anticancer activity of JorA on MIBC and the 3D structures of the molecular interaction of JorA were displayed