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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Investigations of brain-wide functional and structural networks of dopaminergic and CamKIIα-positive neurons in VTA with DREADD-fMRI and neurotropic virus tracing technologies

Fig. 5

Conjunction analysis of global BOLD signal responses in DAT-cre and CamKIIα-cre rats after the chemogenetic activation in VTA with CNO. A Changes of the BOLD signals in both DAT-cre and CamKIIα-cre animals after the chemogenetic activation and the co-localization of the increased BOLD signals were illustrated in yellow, including the Cg, mPFC and Septum; B the increased BOLD signals in the cerebral regions after the chemogenetic activation in DAT-cre (gray) or CamKIIα-cre animals (purple); C the increased BOLD signals in the co-localizations after the chemogenetic activation in DAT-cre or CamKIIα-cre animals. Two-tailed t-test, Ave. ± STD; *p < 0.05; **p < 0.01

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