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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Pharmacological inhibition of demethylzeylasteral on JAK-STAT signaling ameliorates vitiligo

Fig. 4

T-96 exerted immunosuppressive effects primarily by targeting JAK3. A Flow cytometry analysis of IFN-γ, GzmB and PRF expression upon JAK3 knockdown, representative examples (left), and frequency analysis (right). B Flow cytometry for the expression of IFN-γ, GzmB and PRF upon JAK3 overexpression, representative examples (left), and frequency analysis (right). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns not significant

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