Table 1 Demographics and clinical characteristics of the study cohort
From: Oral-microbiome-derived signatures enable non-invasive diagnosis of laryngeal cancers
|  | Entire cohort (N = 153) | Train set (N = 121) | Test set (N = 32) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LSCC (N = 77) | Control (N = 76) | P | LSCC (N = 64) | Control (N = 57) | P | LSCC (N = 13) | Control (N = 19) | P | |||||||
No | % | No | % | No | % | No | % | No | % | No | % | ||||
Age (y) | |||||||||||||||
 ≤ 55 | 12 | 15.6 | 21 | 27.6 | 0.182 | 10 | 15.6 | 16 | 28.1 | 0.242 | 2 | 15.4 | 5 | 26.3 | 0.737 |
 56–70 | 54 | 70.1 | 47 | 61.8 | 45 | 70.3 | 35 | 61.4 | 9 | 69.2 | 12 | 63.2 | |||
 > 70 | 11 | 14.3 | 8 | 10.5 | 9 | 14.1 | 6 | 10.5 | 2 | 15.4 | 2 | 10.5 | |||
Gender (%) | |||||||||||||||
 Male | 71 | 92.2 | 66 | 86.8 | 0.278 | 59 | 92.2 | 50 | 87.7 | 0.412 | 12 | 92.3 | 16 | 84.2 | 0.496 |
 Female | 6 | 7.8 | 10 | 13.2 | 5 | 7.8 | 7 | 12.3 | 1 | 7.7 | 3 | 15.8 | |||
Smoking status | |||||||||||||||
 Smokers | 66 | 85.7 | 27 | 35.5 | < 0.01 | 56 | 87.5 | 21 | 36.8 | < 0.01 | 10 | 76.9 | 6 | 31.6 | 0.012 |
 Nonsmokers | 11 | 14.3 | 49 | 64.5 | 8 | 12.5 | 36 | 63.2 | 3 | 23.1 | 13 | 68.4 | |||
Alcohol | |||||||||||||||
 Drinkers | 45 | 58.4 | 19 | 25.0 | < 0.01 | 39 | 60.9 | 16 | 28.1 | < 0.01 | 6 | 46.2 | 3 | 15.8 | 0.061 |
 Nondrinkers | 32 | 41.6 | 57 | 75.0 | 25 | 39.1 | 41 | 71.9 | 7 | 53.8 | 16 | 84.2 | |||