Fig. 5From: RNA aptamers with specific binding affinity to CD40 (CD40Apt) represents a promising antagonist of the CD40-CD40L signaling for thyroid-associated ophthalmopathy (TAO) treatment in mouseOrbital fibroblast activation and CD40 levels in mice. A–D The levels of CD40, collagen I, TGF-β, and α-SMA in orbital adipose and fibrous tissues examined using Immunohistochemical staining (IHC)Back to article page