Fig. 7From: Improving the cytotoxicity of immunotoxins by reducing the affinity of the antibody in acidic pHWorking model of the regulatory effect of low pH-responsive antibodies on the intracellular behavior of immunotoxins. Low pH-sensitive antibody-based immunotoxins lead to fast degradation in lysosomes, which accelerates the accumulation of free toxin and produces effective cytotoxicity in tumor cellsBack to article page