Fig. 3
From: ST6GALNAC4 promotes hepatocellular carcinogenesis by inducing abnormal glycosylation
ST6GALNAC4 enhanced HCC cells proliferation, migration, and invasion in vivo. Tumor growth curve of stable ST6GALNAC4 knockdown HCCLM3 (A) and MHCC97H (B) in subcutaneous xenografted nude mice models compared with control. Tumor growth curve of stable ST6GALNAC4 overexpressing HCCLM3 (C) and MHCC97H (D) in subcutaneous xenografted nude mice models compared with control. E Tumor weights in subcutaneous xenografted nude mice models were recorded. F Tumors in different group were staining with Ki67 and PCNA. scale bar, 50 \(\mu\)m; magnification, ×200. G Pulmonary metastasis models were constructed with stable ST6GALNAC4 knockdown or overexpressing HCCLM3 cell compared with control. Staining with hematoxylin and eosin revealed tumors. scale bar, 50 \(\mu\)m; magnification, ×200. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. ns, not significant