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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: ST6GALNAC4 promotes hepatocellular carcinogenesis by inducing abnormal glycosylation

Fig. 1

Identification of key glycosyltransferase related to O-glycosylation indicating poor prognosis in HCC. A Partial likelihood deviance of different combinations of variables calculated via the LASSO Cox regression model and LASSO coefficient profiles of candidate genes. B Heatmap of the expression levels of candidate genes. C ROC AUC of the regression model and KM curves of different groups. D KM curves of ST6GALNAC4 in TCGA data sets. E Expression of ST6GALNAC4 in TCGA data sets. F ROC curve analysis of ST6GALNAC4 diagnosis. G IHC staining of ST6GALNAC4 in HCC and adjacent liver tissue (scale bar, 50 \(\mu\)m; magnification, ×400). H IHC score of ST6GALNAC4 in 90 pairs of our own HCC tissue array. I KM curves of ST6GALNAC4 in our own HCC tissue array. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. ns, not significant

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