Fig. 6

TabNet global interpretability analysis using the Shapley Additive Explanations (SHAP) technique. A Summary plot listing radiomics features from top to bottom in a decreasing order of their impact on the model’s decision. The top four most significant features were texture-related features. B Variation of the SHAP value of four selected features with respect to the actual feature value. Homogeneous textures were associated with a higher CD73 expression, as mirrored by the effect of the top-ranking features