| HCs (n = 228) | MS (n = 208) | NMOSD (n = 200) | p-value |
---|---|---|---|---|
Age (years) | 37.0 (21.0) | 36.0 (17.0) | 41.0 (21.5) | 0.003a,c |
Sex (female/male) | 124/104 | 135/73 | 175/25 |  < 0.001a,b,c |
Disease state (relapsing/remitting)* | – | 48/149 | 48/147 | 0.954 |
Disease duration (months) | – | 19.0 (54.0) | 36.0 (52.0) | 0.054 |
Lesion | ||||
 N (%) | – | 208 (100%) | 110 (55%) |  < 0.001 |
 Volume (cm3) | – | 7.6 (16.0) | 1.2 (4.0) |  < 0.001 |
 EDSS | – | 2.0 (2.5) | 3.5 (3.0) |  < 0.001 |
 CVLT†| 52.0 (10.8) | 47.5 (15.0) | 47.0 (14.5) |  < 0.001b,c |
 PASAT†| 51.5 (14.0) | 40.0 (17.0) | 40.0 (18.0) |  < 0.001b,c |
 BVMT†| 28.0 (5.8) | 27.0 (11.8) | 22.0 (12.0) | 0.003c |