Fig. 4
From: Targeting KK-LC-1 inhibits malignant biological behaviors of triple-negative breast cancer
In vivo experiments presented that KK-LC-1 can regulate the malignant biological behaviors of triple-negative breast cancer. A In vivo tumorigenic models of NC and KD nude mice were successfully established. B Display of tumorigenic specimens in NC KD nude mice. C The volume change of tumor formation in nude mice. D Weight of tumor formation in nude mice. E Detection the expression of PI3K/AKT/mTOR pathway related proteins by immunohistochemistry in NC tumors. F Detection the expression of PI3K/AKT/mTOR pathway related proteins by immunohistochemistry in KD tumors. G Detection the expression of Caspase-3 and PCNA by immunohistochemistry in NC tumors. H Detection the expression of Caspase-3 and PCNA by immunohistochemistry in KD tumors. I Detection the expression of KK-LC-1, MAL2, MUC1 by immunohistochemistry in NC tumors. J Detection the expression of KK-LC-1, MAL2, MUC1 by immunohistochemistry in KD tumors. (**P < 0.01)