Chemical treatment | Agonist activity | Antagonist activity |
---|
TCDD | 100 ± 29.14 | 100 ± 28.68 |
TPPU | − 0.70 ± 2.66 | 85.18 ± 31.23 |
- Results are expressed as the mean ± SD of triplicate incubations of each sample and an asterisk (*) indicates those values significantly greater than the background activity in the DMSO blank at P < 0.05 as determined by the Students t-test. Results in this table demonstrate that no chemical significantly induced AHR-dependent reporter gene activity above background activity or antagonized induction by the reference standard, TCDD. (Table 1)