Fig. 4From: Unmasking the biological function and regulatory mechanism of NOC2L: a novel inhibitor of histone acetyltransferaseNOC2L Interacts with P53 on P53-targeted Gene. Upon recruitment by P53, NOC2L regulates the acetylation status in the vicinity of P53-occupying sites. NOC2L inhibits the acetylation of H3/H4 at p53 target promoters. Due to the inhibition of histone acetylation, the transcription of P53 target gene is inhibitedBack to article page