Fig. 6

Venn diagrams of WebGestalt analysis with ORA. The Venn diagram in figure A shows the difference in sets of transcripts (that govern pathways, cellular and molecular functions and other biological processes) targeted by miR in whole CSF (blue circle) and CSF-derived EV (yellow circle). The Venn diagram in figure B displays the same information for whole serum versus serum-derived EV. The WebGestalt analysis was performed with the ORA enrichment method. Only gene sets significantly different in both, FDR < 0.05 and p < 0.05, are depicted. For further information please also refer to Additional file 3: Tables S7 and S8