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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: In vivo detection of dysregulated choline metabolism in paclitaxel-resistant ovarian cancers with proton magnetic resonance spectroscopy

Fig. 6

Regulation of GPCPD1 and GDE1 on PTX-resistance in ovarian cancers. Volcano plot showing differential expressed proteins between the OV and OV_PTX groups (A). Schematic description of Cho metabolism (B). The qRT-PCR showing the expression of GPCPD1 and GDE1 in the OV and OV_PTX groups (C). **, P < 0.01. Correlation heat map of differential metabolites between GPCPD1 and GDE1 mRNA, in vivo and ex vivo differential metabolites (D). GPCPD1 glycerophosphocholine phosphodiesterase 1, GDE1 glycerophosphodiester phosphodiesterase 1

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