Fig. 5
Forest plots of the effects of PAG versus AG in terms of PFS by C3M/PRO-C3 ratio in ‘HA-high’ and ‘HA-low’ subgroups in Stage 1 + 2 of HALO 109-202. C3M/PRO-C3 ratio subgroups were defined by the median cut-off from stage 1 in patients presenting with either HA-high (top) or HA-low (bottom) tumor biopsies measured with an affinity histochemistry assay previously described [35]