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Table 3 15 hub genes identified by five algorithms of cytoHubba

From: Three hematologic/immune system-specific expressed genes are considered as the potential biomarkers for the diagnosis of early rheumatoid arthritis through bioinformatics analysis

Gene symbol

Description

log2FC

Q value

Regulation

CXCL13

C–X–C motif chemokine ligand 13

2.846

0.012

Up

CD52

CD52 molecule

1.928

0.004

Up

GZMA

Qranzyme A

1.753

0.022

Up

CD27

CD27 molecule

1.419

0.004

Up

CEP55

Centrosomal protein 55

1.264

0.01

Up

SKA3

Spindle and kinetochore associated complex subunit 3

1.215

3.03E−07

Up

IL21R

Interleukin 21 receptor

1.208

7E−04

Up

DLGAP5

DLG associated protein 5

1.172

0.027

Up

PRC1

Protein regulator of cytokinesis 1

1.112

0.042

Up

EOMES

eomesodermi

1.108

0.031

Up

TTK

TTK protein kinas

1.065

0.006

Up

CDCA8

Cell division cycle associated 8

1.049

1.74E−08

Up

UHRF1

Ubiquitin-like with PHD and ring finger domains 1

1.048

0.016

Up

KIAA0101

PCNA clamp associated factor

1.017

0.013

Up

FNBP1L

Formin binding protein 1 like

−1.325

0.004

Down

  1. Annotation: FC: fold change, Q value: adjust P-value. The gene symbol in bold indicates eight hematologic/immune system-specific expressed hub genes