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Table 1 DNA integrity: size of peaks 1 and 2 (A: MagNA Pure 24 System, B: IDEAL, C: LabTurbo 24 AB; D: Chemagic 360D)

From: Qualitative and quantitative comparison of cell-free DNA and cell-free fetal DNA isolation by four (semi-)automated extraction methods: impact in two clinical applications: chimerism quantification and noninvasive prenatal diagnosis

Isolation method

A

B

C

D

Peak 1 (pB)

129

165

165

165

128

163

165

165

129

166

167

167

93

164

164

166

164

165

167

Mean (pB)

119.75

164.40

165.20

166.00

SD

17.84

1.14

1.10

1.00

CV

0.15

0.01

0.01

0.01

Min (pB)

93.00

163.00

164.00

165.00

Max (pB)

129.00

166.00

167.00

167.00

P

< 0.005

p BCD

 

0.104

Peak 2 (pB)

307

312

314

301

308

314

312

311

319

309

309

314

305

310

316

Mean (pB)

306.80

310.00

315.40

SD

4.15

1.58

2.19

CV

0.01

0.01

0.01

Min (pB)

301.00

308.00

314.00

Max (pB)

312.00

312.00

319.00

p BCD

 

0.00158