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Table 2 Distribution of Injury severity, neurosurgical interventions and MRI findings at presentation in acute cervical SCI patients

From: Serial plasma DNA levels as predictors of outcome in patients with acute traumatic cervical spinal cord injury

 

Severity of traumatic spinal cord injury

Severe (n = 33) (JOA score 0–7)

Moderate (n = 5) (JOA score 8–11)

Mild (n = 6) (JOA score 12–15)

Injury level

 C1–C4

23

3

2

 Below C4

10

2

4

ISS score at presentation

 0–8

0

0

1

 9–15

2

2

2

 16–24

20

3

3

 > 24

11

0

0

MRI findings at presentation

 Spinal cord swelling

2

3

3

 Spinal cord edema

6

2

3

 Spinal cord contusion

18

0

0

 Intramedullary hemorrhage

7

0

0

Neurosurgical intervention

 Emergent surgery (< 24 h)

  Laminectomy + posterior fixation

18

0

0

  ACDF ± corpectomy

3

1

1

 Elective surgery (> 24 h)

  Laminectomy + posterior fixation

2

0

0

  ACDF ± corpectomy

20

3

2

 Laminectomy + ACDF

1

0

0

Plasma DNA at presentation, median (IQR)

 Plasma nuclear DNA (ng/ml)

53.2 (31.5, 104.8)

15.2 (10.0, 82.7)

24.4 (14.9, 26.9)

 Plasma mitochondrial DNA (ng/ml)

45.0 (22.3, 137.2)

23.3 (11.4, 135.9)

36.8 (20.8, 99.7)

  1. JOA Japanese Orthopaedic Association, ISS Injury Severity Score, MRI magnetic resonance imaging, ACDF anterior cervical discectomy and fusion, IQR interquartile range, DNA deoxyribonucleic acid