| Severity of traumatic spinal cord injury | ||
---|---|---|---|
Severe (n = 33) (JOA score 0–7) | Moderate (n = 5) (JOA score 8–11) | Mild (n = 6) (JOA score 12–15) | |
Injury level | |||
 C1–C4 | 23 | 3 | 2 |
 Below C4 | 10 | 2 | 4 |
ISS score at presentation | |||
 0–8 | 0 | 0 | 1 |
 9–15 | 2 | 2 | 2 |
 16–24 | 20 | 3 | 3 |
 > 24 | 11 | 0 | 0 |
MRI findings at presentation | |||
 Spinal cord swelling | 2 | 3 | 3 |
 Spinal cord edema | 6 | 2 | 3 |
 Spinal cord contusion | 18 | 0 | 0 |
 Intramedullary hemorrhage | 7 | 0 | 0 |
Neurosurgical intervention | |||
 Emergent surgery (< 24 h) | |||
  Laminectomy + posterior fixation | 18 | 0 | 0 |
  ACDF ± corpectomy | 3 | 1 | 1 |
 Elective surgery (> 24 h) | |||
  Laminectomy + posterior fixation | 2 | 0 | 0 |
  ACDF ± corpectomy | 20 | 3 | 2 |
 Laminectomy + ACDF | 1 | 0 | 0 |
Plasma DNA at presentation, median (IQR) | |||
 Plasma nuclear DNA (ng/ml) | 53.2 (31.5, 104.8) | 15.2 (10.0, 82.7) | 24.4 (14.9, 26.9) |
 Plasma mitochondrial DNA (ng/ml) | 45.0 (22.3, 137.2) | 23.3 (11.4, 135.9) | 36.8 (20.8, 99.7) |