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Table 2 Association of SDF-1 levels, CXCR4+ cells and mRNA expression of CXCR4 and CXCR7 receptors in the BM

From: The homing of bone marrow stem cells is differentially activated in ischemic and valvular heart diseases and influenced by beta-blockers

Study variables

IHD

VHD

r/P/n

r/P/n

SDF-1 vs. CXCR4+ cells

− 0.10/0.87/5

1.00*/< 0.05/4

SDF-1 vs. CXCR4 mRNA

0.60/0.20/6

− 0.21/0.62/7

SDF-1 vs. CXCR7 mRNA

− 0.71/0.11/6

0.64/0.11/7

CXCR4+ cells vs. CXCR4 mRNA

− 0.70/0.18/5

0.80/0.20/4

CXCR4+ cells vs. CXCR7 mRNA

0.00/1.00/5

0.40/0.60/7

CXCR4+ mRNA vs. CXCR7 mRNA

− 0.42/0.39/6

− 0.21/0.64/7

  1. Stromal-derived-factor-1 (SDF-1, pg/mL); CXCR4+ populations (% CD184+ cells); CXCR4 and CXCR7 mRNA expressed in log10 of the relative expression
  2. r Spearman’s correlation coefficient, P significance level, n sample, IHD ischemic heart disease, VHD valvular heart disease
  3. * Strong direct correlation (P ≤ 0.05)
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Journal of Translational Medicine

ISSN: 1479-5876

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