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Table 2 Comparison of cell cycle distribution in exponentially growing monolayers and spheroids studied as a function of age.

From: Establishment and characterization of multicellular spheroids from a human glioma cell line; Implications for tumor therapy

Age of spheroids in days G0/G1 Total S Phase Cells S-Positive Cells S-Negative Cells G2/M
Monolayers 48 ± 3 40 ± 1 40 ± 1 0 12 ± 1
Plateau 72 ± 2 3 ± 2 3 ± 2 0 25 ± 4
07 59 ± 2 20 ± 3 18 ± 3 2 ± 0.5 21 ± 2
14 59 ± 2 20 ± 1 9 ± 1 11 ± 1 21 ± 1
21 56 ± 3 19 ± 2 6 ± 2 13 ± 1 25 ± 3
28 58 ± 4 19 ± 1 5 ± 1 14 ± 1 23 ± 1
  1. Note: All values are mean ± SD of 3 observations from three experiments