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Table 1 Body and kidney weights of Sham, 2K1C and 2K1C-sildenafil treated mice 28 days after renal artery clipping

From: Sildenafil ameliorates oxidative stress and DNA damage in the stenotic kidneys in mice with renovascular hypertension

Parameters

Sham (n = 8)

2K1C (n = 10)

2K1C sildenafil (n = 8)

Body weight (g)

26 ± 0.5

24 ± 0.4*

26 ± 0.3#

Clipped kidney dry weight/body weight (mg/g)

1.63 ± 0.07

0.96 ± 0.17**

1.5 ± 0.04#

Nonclipped kidney dry weight/body weight (mg/g)

1.78 ± 0.04

2.02 ± 0.06*

1.77 ± 0.05#

Clipped kidney weight/nonclipped kidney weight ratio

0.91 ± 0.04

0.54 ± 0.09**

0.78 ± 0.06#

Kidney cell viability (%)

99 ± 0.13

94 ± 1.5**

98 ± 0.6#

  1. Values are the means ± SEM. *p < 0.05 and **p < 0.01 compared with Sham group; # p < 0.05 compared with 2K1C group.