Figure 3From: Sildenafil ameliorates oxidative stress and DNA damage in the stenotic kidneys in mice with renovascular hypertension Sildenafil ameliorates oxidative stress of the stenotic kidney cells in renovascular hypertensive mice. Representative flow cytometry histograms show the fluorescence intensities of DHE (panel A), DCF-DA (panel B) and DAF-2/DA (panel D) stained cells from the Sham (n = 10), 2K1C (n = 10) and 2K1C-sildenafil (n = 10) mice. Bar graphs show the geometric mean intensity of DHE (panel C, white bars) and DCF-2/DA (panel C, color bars) and NO (panel E) production in the stenotic kidney. *p < 0.05 and **p < 0.01 (ANOVA).Back to article page