Figure 3
From: Cardioprotective effects of lixisenatide in rat myocardial ischemia-reperfusion injury studies
![Figure 3](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2F1479-5876-11-84/MediaObjects/12967_2012_Article_1487_Fig3_HTML.jpg)
Effect of long-term treatment with either lixisenatide or ramipril after transient ischemia-reperfusion injury on heart morphology. (A) Picrosirius red staining at the papillary muscle level of representative animals, Bar = 5 mm; (B) quantification of left ventricular fibrotic to total area; (C) thickness of the left ventricular, septal and right ventricular wall; and (D) gene expression analysis by realtime PCR of selected fibrosis genes. *) denotes p < 0.05 versus sham and #) p < 0.05 versus placebo.