Characteristics | FH mutation (n = 40) | No FH mutation (n = 65) | p value |
---|---|---|---|
Age, years | 29.9 ± 7.57 | 32.78 ± 3.70 | 0.029 |
Male, n (%) | 35 (87.5) | 64 (98.5) | 0.019 |
BMI, kg/(m2) | 25.16 ± 5.06 | 31.35 ± 24.85 | 0.133 |
Family history of premature CAD, n (%) | 9 (22.5) | 11 (16.9) | 0.480 |
History of MI, n (%) | 21 (52.5) | 31 (47.7) | 0.632 |
Currently smoking, n (%) | 20 (50.0) | 50 (76.9) | 0.004 |
Alcohol drinker, n (%) | 10 (25.0) | 32 (49.2) | 0.014 |
Hypertension, n (%) | 9 (25.0) | 37 (56.9) | 0.001 |
DM, n (%) | 4 (10.0) | 13 (20.0) | 0.177 |
Statin, n (%) | 29 (72.5) | 52 (80.0) | 0.374 |
TG, mmol/L | 1.95 ± 0.89 | 1.57 ± 0.7 | 0.025 |
TC, mmol/L | 7.78 ± 4.01 | 6.14 ± 8.97 | 0.410 |
HDL-C, mmol/L | 0.86 ± 0.27 | 0.92 ± 0.26 | 0.249 |
LDL-C, mmol/L | 7.56 ± 4.49 | 4.61 ± 1.63 | < 0.001 |
Lp(a), mg/dL | 327.09 (107.75–532.10) | 110.59 (55.03–404.98) | 0.033 |
Xanthoma, n (%) | 10 (25.0) | 2 (3.1) | 0.001 |