Table 2 Amino acid concentrations in preoperative serum
Amino acid | Serum concentration [μg/mL] | Fold difference | P-value | Trend | ||
|---|---|---|---|---|---|---|
|  |  | BrCA [n = 41] | HD [n = 9] |  |  |  |
Aspartic acid | Asp | 22.69 ± 8.4 | 15.14 ± 6.9 | 1.50 |  |  |
Glutamic acid | Glu | 159.98 ± 59.0 | 86.86 ± 27.4 | 1.84 | 0.021 | Higher in BrCA |
Asparagine | Asn | 54.68 ± 14.8 | 47.96 ± 17.4 | 1.14 |  |  |
Serine | Ser | 168.34 ± 41.7 | 139.19 ± 45.2 | 1.21 | 0.032 | Higher in BrCA |
Glutamine | Gln | 571.81 ± 174.3 | 393.82 ± 113.7 | 1.45 | 0.017 | Higher in BrCA |
Citrulline | Cit | 41.20 ± 12.2 | 33.56 ± 8.5 | 1.23 |  |  |
Arginine | Arg | 162.63 ± 44.7 | 124.16 ± 47.6 | 1.31 |  |  |
Alanine | Ala | 571.50 ± 167.7 | 349.48 ± 119.7 | 1.64 | 0.005 | Higher in BrCA |
Tyrosine | Tyr | 94.77 ± 31.3 | 63.18 ± 36.5 | 1.50 |  |  |
Valine | Val | 316.15 ± 68.1 | 205.66 ± 75.2 | 1.54 | 0.003 | Higher in BrCA |
Phenylalanine | Phe | 91.51 ± 20.8 | 61.92 ± 22.2 | 1.48 | 0.015 | Higher in BrCA |
Isoleucine | Ile | 93.77 ± 26.6 | 58.43 ± 24.6 | 1.60 | 0.011 | Higher in BrCA |
Leucine | Leu | 157.89 ± 39.4 | 105.38 ± 40.2 | 1.50 | 0.013 | Higher in BrCA |
Ornithine | Orn | 115.55 ± 35.5 | 93.53 ± 36.1 | 1.24 |  |  |
Lysine | Lys | 342.37 ± 119.9 | 250.04 ± 89.5 | 1.37 |  |  |