Fig. 7

Effects of isoproterenol (ISO) and PSELT on Selenoprotein T (SELENOT) intracellular and extracellular levels in human cardiomyocytes. A Intra-cardiomyocyte levels of SELENOT in AC16 cells exposed to vehicle (saline, NaCl 0.9%) indicated as a CTRL, isoproterenol (ISO) (100 µM), ISO + PSELT and PSELT (5 nM) for 24–48-72–96 h. B SELENOT levels in cell culture medium (supernatant) of AC16 cardiomyocytes exposed to vehicle (saline, NaCl 0.9%) indicated as a CTRL, isoproterenol (ISO) (100 µM), ISO + PSELT and PSELT (5 nM) for 24–48-72–96 h. Data are expressed as means ± SEM. Significant differences were detected by one-way ANOVA and Newman-Keuls multiple comparison test. *p < 0.05; **p < 0.01; ***p < 0.001