Fig. 3

Effect of PSELT on cardiac function and infarct size (IS) of Langendorff-perfused rat hearts subjected to I/R injury. A dLVP and B LVEDP variations. Gray boxes indicate ischemic administration (Bonferroni multiple comparison test). dLVP = 21.98% of total variation between groups (p < 0.001); LVEDP = 19.46% of total variation between groups (p < 0.001). Inset histograms show dLVP and LVEDP at the end of reperfusion. Data are expressed as changes of dLVP and LVEDP values (millimeters of mercury, mmHg) from stabilization to the end of reperfusion with respect to the baseline values for WST, WST + PSELT, SHHF, SHHF + PSELT groups (n = 6 hearts/group). Significant differences were detected by one-way ANOVA and Newman-Keuls multiple comparison test. **p < 0.01, ***p < 0.001. C Infarct size (IS) expressed as a percentage of the LV mass (% IS/LV) in WST, WST + PSELT, SHHF, SHHF + PSELT groups. Significant differences were detected by one-way ANOVA and Newman-Keuls multiple comparison test. **p < 0.01, ***p < 0.001