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Table 2 Results of supplementary xWAS analyses for the five neuropsychiatric disorders conducted in this study

From: xWAS analysis in neuropsychiatric disorders by integrating multi-molecular phenotype quantitative trait loci and GWAS summary data

Method

xQTL Type

Datasets

Tissue

SCZ

BP

ADHD

ASD

MDD

FUSION

eQTL

GTEx_V8 (EUR)

Non-brain

5216

1566

237

197

592

Brain

1396

398

68

111

157

PsychENCODE

Brain

130*

41

2*

2*

26

sQTL

CMC

Brain

149

45

4*

4

25

pQTL

Banner

Brain

47

11

1

0

9

ROSMAP

Brain

43

13

2

0

8

m6AQTL

Brain

Brain

18

8

2

1

6

Lung

Non-brain

25

7

0

0

2

Muscle

Non-brain

18

6

1

0

4

SMR

eQTL

PsychENCODE

Brain

70*

24

3

3*

7

eQTLGen

Non-brain

57*

22

3*

0*

18

sQTL

BrainMeta v2

Brain

82

21

0

0

13

GTEx_V8 (EUR)

Non-brain

1016

277

7

0

238

Brain

288

60

10

0

57

pQTL

ROSMAP

Brain

12

0

0

0

5

mQTL

Brain-mMeta

Brain

139

32

0*

0

22

LBC_BSGS

Non-brain

109

70

0

0

114

m6AQTL

Brain

Brain

0

0

0

0

0

Lung

Non-brain

1

0

0

0

0

Muscle

Non-brain

0

0

0

0

0

  1. The number denotes the number of significant genes; * denotes the results have been reported by published studies and the others were analyzed by this study