Fig. 4From: TP53 missense mutation reveals gain-of-function properties in small-sized KRAS transformed pancreatic ductal adenocarcinomaTP53 knock-out was associated with lower invasiveness compared with TP53 missense mutations. AÂ Transwell migration assay of PANC-1 and CFPAC-1 cells after knock-out of the TP53 missense mutation. BÂ Wound healing assays performed using PANC-1 and CFPAC-1 cells after knock-out of the TP53 missense mutation. CÂ Validation of the knock-out of the TP53 missense mutation by qRT-PCR.Back to article page