Fig. 2

Brain cortical levels of Histone deacetylase 2 (HDAC2). Representative merge images of DAPI–DNA blue staining of cells' nuclei and HDAC2 protein-red staining in SBN/y and SBH/y s at three time points: baseline, 6 months, and 9 months on RD or HSD. Scale bar: 50 µm. B IF analysis of cortical HDAC2 protein ratio level (N = 6–7, per group). Mean ± SEM. Three-way ANOVA was followed by Tukey’s multiple comparison test. ^*P < 0.05, ^***P < 0.001