Fig. 5

The performance evaluation of the CTCP model for predicting RFS in the validation cohort. A The Calibration curves reveal the concordance between model prediction and actual distribution for 2 year RFS. Gray line: reference line. Red line: the prediction curve generated by this model. B The DCA curves show the net clinical benefit of the application of the CTCP model to predict 2 year RFS. C Comparison of the CTCP model with ctDNA using ROC analyses for predicting 2 year RFS. D The recurrence rate for CRC patients stratified by the CTCP model. E Kaplan–Meier curves of RFS for CRC patients stratified by the CTCP model. CTCP ctDNA and clinicopathological risk factors, CRC colorectal cancer, RFS recurrence-free survival, ctDNA circulating tumor DNA, ROC receiver operating characteristic, DCA decision curve analysis