Fig. 3
From: Triple blockade of Ido-1, PD-L1 and MEK as a potential therapeutic strategy in NSCLC
A mRNA expression level of IDO-1 in a panel of NSCLC cell lines: epithelial (E) cells (H441, 322 M, HCC4006) versus mesenchymal (M) cells (H1299, H460, A549). Results were normalized to 18S mRNA and analyzed by ΔCt method. B Comparison of phosphorylated PKCa and total levels between E and M NSCLC cell lines. Fold change in expression and p-value by t-test are indicated. C Comparison of IDO1 and CD274 mRNA expression between E and M tumors in the TCGA LUAD cohort. Fold change in expression and p-value by t-test are indicated