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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Association of peripheral basophils with tumor M2 macrophage infiltration and outcomes of the anti-PD-1 inhibitor plus chemotherapy combination in advanced gastric cancer

Fig. 1

Assessment of peripheral basophils prior to treatment with the anti-PD-1 inhibitor plus chemotherapy combination in patients with advanced gastric cancer. a peripheral basophil counts from cycle 1 to cycle 6 of patients according to their disease response. b Peripheral basophil counts of patients with gastric cancer who experienced complete/partial response (CR/PR) or stable/progressive disease (SD/PD) as the best objective response to the anti-PD-1 inhibitor plus chemotherapy combination. c peripheral basophil counts of patients with CR, PR, SD, or PD. d proportions of patients with CR, PR, SD, or PD in the low-basophil and high-basophil groups. e Linear correlation between peripheral basophil counts and PD-L1 expression. f A comparison of peripheral basophil counts between the dMMR, EBV + , and EBV−/pMMR subgroups. PD-1: programmed death-1; PD-L1: programmed death ligand-1; dMMR: deficient mismatch repair; EBV: Epstein-Barr Virus; pMMR: proficient mismatch repair. Quantitative data are presented as the mean ± SEM. ns indicates not significant, *P < .05, **P < .01

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