Fig. 5
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12967-019-2094-x/MediaObjects/12967_2019_2094_Fig5_HTML.png)
Numerical simulation of the impulse response function of one osteolytic lesion, sonicated with the focal point symmetrically positioned in the center of the cortical breakthrough, axial bone diameter 12 mm. a Temperature elevation at the end of a short HIFU sonication isolating only the cortical source, followed by a free evolution of b 40 s and c 60 s. d Temperature elevation at the end of a short HIFU sonication considering the cumulated source of heating followed by a free evolution of e 40 s and f 60 s. Temperature color bar and graphical distance scale are provided